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卵巢癌是目前早期诊断率低而死亡率最高的一种常见妇科恶性肿瘤,约60%～70%的患者确诊时已为晚期。对于晚期卵巢癌患者的治疗,除手术外,化疗也是一个极其重要的手段。本文旨在综合关于晚期卵巢癌化疗上的一些最新研究成果,以供临床医师决策参考。1 晚期卵巢癌的一线化疗药物1.1 铂类以DDP(顺铂)为基础的联合化疗目前已被广泛应用于治疗卵巢癌。然而,由于DDP具有不可逆的肾毒性、严重的
Ovarian cancer is a common gynecologic malignancy with the lowest early diagnosis rate and the highest mortality rate. About 60% -70% of the patients have been diagnosed late. For the treatment of patients with advanced ovarian cancer, in addition to surgery, chemotherapy is also an extremely important means. This article aims to synthesize some of the latest research results on advanced ovarian cancer chemotherapy for decision-making clinicians reference. 1 first-line chemotherapy for advanced ovarian cancer 1.1 Platinum Combined chemotherapy based on DDP (cisplatin) has now been widely used to treat ovarian cancer. However, due to irreversible nephrotoxicity of DDP, serious