过氧化物酶增殖体活化受体(peroxisome proliferator-activated receptors,PPARs)是能量代谢的重要调节因子,除了增强胰岛素的敏感性外,还调控脂肪的积聚、细胞的增生和炎性反应。近年研究发现人类生殖系统中存在PPARs表达,其参与卵巢雌孕激素的合成并影响受孕,通过影响组织的重塑方式调节卵泡的发生、排卵和黄体的发育,参与胚胎种植和发育及调节胎盘功能维持妊娠等。 Peroxisome proliferator-activated receptors (PPARs) are important regulators of energy metabolism, in addition to enhancing insulin sensitivity, but also regulate fat accumulation, cell proliferation and inflammatory response. In recent years, studies have found that the human reproductive system exists PPARs expression, which is involved in ovarian estrogen and progesterone synthesis and affect the pregnancy, by affecting the way of tissue remodeling follicular development, ovulation and the development of the corpus luteum, embryo implantation and development and regulation of placental function To maintain the pregnancy.