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为探讨严重急性呼吸综合征 (SARS)治疗过程中糖皮质激素的应用时机、疗程和效果 ,对 7例 SARS患者 (其中男 4例 ,女 3例 ,平均年龄 31.3岁 )应用糖皮质激素治疗 ,甲泼尼龙平均剂量为 12 6 m g/ d,平均疗程 7.8d;口服泼尼松平均疗程 12d。结果高热患者在治疗后 2 d体温恢复正常 ,肺部进行性病变者在 3~ 5 d内有所恢复 ,疗程结束时病灶明显吸收 ,无 1例患者发生呼吸衰竭。提示糖皮质激素对改善 SARS中毒症状 ,阻止病情进展有一定疗效。
To investigate the timing, course of treatment and effect of glucocorticoid in the treatment of severe acute respiratory syndrome (SARS), 7 patients with SARS (including 4 males and 3 females with an average age of 31.3 years) were treated with glucocorticoid, The average dose of methylprednisolone was 12 6 mg / d with an average duration of 7.8 days. The average course of oral prednisone was 12 days. Results The patients with hyperthermia returned to normal body temperature 2 days after treatment. Patients with progressive lung disease recovered within 3 to 5 days. At the end of the treatment, the lesions were obviously absorbed and no respiratory failure occurred in 1 patient. Suggest that glucocorticoids to improve the symptoms of SARS poisoning, to prevent the progression of the disease have a certain effect.