论文部分内容阅读
目的探讨1例稀有血型结肠癌患者紧急抢救输血时因不规则抗体存在导致交叉配血困难而采用特殊情况紧急抢救输血推荐方案的可行性。方法标本首次血型检测采用全自动血型仪检测血型(微孔板法),并用试管法复查患者血型;微柱凝胶抗球蛋白法、盐水法、聚凝胺法、试管抗人球蛋白法做抗体筛查和交叉配血。结果患者血型为A型,Rh表型为ccDEE型,血清中含有抗-C和抗-e不规则抗体;经过Rh表型筛选,从O型供者中找到Rh表型为ccDEE悬浮红细胞1 U,从浙江省血液中心的A型供者中筛查到Rh表型为ccDEE悬浮红细胞3 U,输注后12 h检测血红蛋白61 g/L,提示输注有效。有效地缓解了患者的贫血症状,无输血不良反应。结论对于因不规则抗体存在导致配血困难而又需紧急输血抢救的肿瘤患者,在ABO血型同型无法满足供应时,可筛选O型Rh表型一致且交叉配血试验阴性的供者红细胞输注。
Objective To investigate the feasibility of using a special emergency rescue blood transfusion protocol in one case of rare blood group colon cancer patients due to the irregular cross-matching of blood due to irregular antibodies. Methods The first blood type test was performed on blood type (microplate method) by automatic blood type analyzer, and the blood type of patients was examined by test tube method. The microcolumn gel antiglobulin method, saline method, polybrene method and in vitro anti-human globulin method Antibody screening and cross-matching blood. Results The patient’s blood type was A, the Rh phenotype was ccDEE, and the serum contained anti-C and anti-e irregular antibodies. , From the A blood donors in Zhejiang Province, Rh type was screened to be 3 U of erythrocytes with ccDEE suspension and 61 g / L of hemoglobin at 12 h after infusion, indicating that infusion is effective. Effectively alleviate the symptoms of anemia in patients with no adverse transfusion reactions. CONCLUSIONS: For patients with tumors that require urgent blood transfusion due to the presence of irregular antibodies, they can screen for donor red blood cell transfusions with consistent O-Rh phenotype and negative cross-pairing test if the ABO blood group is unable to meet supply .