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目的:分析早产并膜早破发生的原因及对母婴的影响。方法:2010年6月～2011年12月收治早产并膜早破患者128例,对情况进行回顾性分析。结果:28～34周组的新生儿并发RDS、窒息、肺炎、高胆红素血症的发生率大大高于35～36周组,死亡率与死胎的发生率高于35～36周组,两组比较差异具有显著性,有统计学意义(P<0.05)。早产并膜早破患者的原因以人流史为主,孕妇有人流史71例(55.47%),其次为臀位22例(17.19%),其排列顺位依次是人流史、臀位、双胎妊娠、子宫畸形、妊娠高血压、胎盘前置、妊娠高肝内胆汁瘀积症与死胎。结论:人流史是导致早产并膜早破发生的危险因素,PPROM发生时间越早,新生儿预后越差,并发症越多。早产并膜早破发生后,应采取有效干预措施,进行产时监护,以减少新生儿死亡及并发症的发生。
Objective: To analyze the causes of premature rupture of membranes and premature rupture of membranes and their effects on maternal and infant. Methods: From June 2010 to December 2011, 128 cases of premature rupture of membranes and rupture of membranes were retrospectively analyzed. Results: The incidence of neonatal complicated with RDS, asphyxia, pneumonia and hyperbilirubinemia in 28-34 weeks group was much higher than that in 35-36 weeks group, and the incidence of death and stillbirth was higher than those in 35-36 weeks group, The difference between the two groups was significant and statistically significant (P <0.05). The causes of premature rupture of membranes and premature rupture of membranes were mainly in the history of abortion. Among pregnant women, there were 71 cases (55.47%) with abortion, followed by 22 cases (17.19%) with breech, followed by the abortion history, breech, twins Pregnancy, uterine malformations, pregnancy-induced hypertension, placenta previa, high intrahepatic cholestasis of pregnancy and stillbirth. Conclusion: The history of human circulation is the risk factor of premature rupture of membranes and premature rupture of membranes. The earlier the PPROM occurs, the worse the prognosis of neonates and the more complications. After premature rupture of membranes and premature rupture of membranes, effective interventions should be taken to monitor during labor to reduce the neonatal mortality and complications.