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目的 探讨因绒毛膜癌(绒癌)脑转移而急诊行开颅手术患者的诊断、治疗和预后。方法 回顾性分析1985年1月至2004年1月, 13例绒癌脑转移瘤周围出血导致颅内压急剧增高、濒临脑疝而急诊行开颅减压及转移瘤切除术,并于术后进行多药联合方案化疗患者的资料。结果13例患者中, 7例(54% )完全缓解, 5例(38% )部分缓解, 1例(8% )患者因病情进展而死亡。经随诊, 13例患者共存活10例(77%, 10 /13),死亡3例(23%, 3 /13)。结论 对颅内压过高、颅内出血、濒临脑疝的绒癌脑转移患者,急诊行开颅手术并进行化疗,是挽救患者生命的重要治疗方法。
Objective To investigate the diagnosis, treatment and prognosis of patients undergoing craniotomy due to choriocarcinoma (choriocarcinoma) brain metastases. Methods A retrospective analysis of January 1985 to January 2004, 13 cases of choriocarcinoma around the brain metastases led to a sharp increase in intracranial pressure, threatened with hernia and emergency craniotomy decompression and metastases resection, and after surgery To carry out multi-drug combination chemotherapy patients information. Results Of the 13 patients, 7 (54%) were completely relieved, 5 (38%) partially relieved and 1 (8%) died due to the progression of the disease. After follow-up, 13 patients survived in 10 cases (77%, 10/13) and 3 died (23%, 3/13). Conclusions For patients with intracranial hypertension, intracranial hemorrhage and brain herniation with malignant brain metastases, emergency craniotomy and chemotherapy are important treatments to save the lives of patients.