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为了探讨治疗血吸虫病药物双羟萘酸副品红、粗制及精制盐酸副品红以及双羟萘酸钠有否致突变作用,我们用了鼠伤寒沙门氏菌/微粒体系统进行了诱变试验(即Ames试验);同时亦进行了小鼠骨髓微核试验.现将结果报道如下:
In order to explore whether schistosomiasis drug parapangone, crude and refined paraquat and sodium pamoate were mutagenic, we used the S. typhimurium / microsome system to mutagenize That Ames test); also conducted a mouse bone marrow micronucleus test now report the results as follows: