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观察慢性肾衰血透患者幽门螺杆菌感染情况。方法 :采用免疫印迹法检测 80例慢性肾衰组和 82例健康对照组的血清幽门螺杆菌 (Helicobacterpylori,Hp)抗体。结果 :80例慢性肾衰患者中Hp抗体阳性者5 7例 (71.2 5 % ) ,其中Ⅰ型 31例 (38.75 % )、Ⅱ型 2 6例 (32 .5 % ) ,而Hp抗体阴性 2 3例 (2 8.75 % )。而 82例健康对照者中有 5 3例 (6 4 .6 % )Hp抗体为阳性 ,其中Ⅰ型 2 9例 (35 .4 % )、Ⅱ型 2 4例 (2 9.2 % ) ,抗体阴性者 2 9例 (35 .4 % )。两组比较无统计学差异 (P >0 .0 5 )。结论 :慢性肾衰Hp感染与正常人群之间无明显差异 ,Hp感染可能与慢性肾衰发病无关。
Observe Helicobacter pylori infection in patients with chronic renal failure. Methods: Serum Helicobacter pylori (Hp) antibody was detected in 80 chronic renal failure patients and 82 healthy controls by Western blotting. Results: Among 80 patients with chronic renal failure, 57 (71.2%) had Hp antibody positive, of which 31 cases were type I (38.75%), 26 cases were type II (32.5%), while Hp antibodies were negative Example (2 8.75%). Among 82 healthy controls, 53 (6.4%) were positive for Hp antibodies, of which 29 cases were type I (35.4%), 24 cases were type II (22.9%), and the antibody negative 29 cases (35.4%). There was no significant difference between the two groups (P> 0.05). Conclusion: There is no significant difference between Hp infection of chronic renal failure and normal population. Hp infection may not be related to the incidence of chronic renal failure.