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目的分析脑卒中后继发癫痫的临床特征,发病机制及预后。方法对58例脑卒中后继发癫痫患者的癫痫发作时间、类型,卒中类型,癫痫与病灶部位间的关系进行回顾性分析。结果脑卒中后癫痫发生率7.39%(58/785),其中,早发型癫痫占81%(47/58),迟发型癫痫占19%(11/58);早发型癫痫发作中全身发作占72.34%(34/47),迟发型癫痫发作中部分发作占72.73%(8/11);皮层病灶继发癫痫占68.97%(40/58),皮层下病灶继发癫痫占31.03%(18/58),两者比较差异具有统计学意义(P<0.05)。结论脑卒中后继发癫痫以早发型为主,以皮层病灶多见;早发型癫痫以全身发作为主,迟发癫痫以部分发作为主。
Objective To analyze the clinical characteristics, pathogenesis and prognosis of post-stroke secondary epilepsy. Methods A retrospective analysis was performed on the relationship between epileptic seizure time, type, stroke type, epilepsy and the location of the lesion in 58 patients with secondary epilepsy after stroke. Results The incidence of post-stroke epilepsy was 7.39% (58/785), of which 81% (47/58) were early-onset epilepsy and 19% (11/58) with delayed-type epilepsy. The incidence of seizures in early-onset seizures was 72.34 % (34/47), partial seizures in delayed seizures accounted for 72.73% (8/11), subcortical seizures accounted for 68.97% (40/58), subcortical seizures accounted for 31.03% (18/58) ), The difference between the two was statistically significant (P <0.05). Conclusions Post-stroke secondary epilepsy is predominantly early-onset and more common in cortical lesions. Early-onset epilepsy is predominantly systemic and late-onset epilepsy is predominantly paroxysmal.