论文部分内容阅读
目的分析本地区各孕周唐氏征筛查人群年龄、体重、孕次等分布情况,对孕周与产前筛查效率的关系进行分析,以期发现本地区效率较高的筛查孕周或孕周段。方法回顾性分析本院5179例孕16～20+6周产前筛查的孕妇三联血清标志物检测结果,对筛查出唐氏综合征高风险孕妇行羊水细胞染色体检查确诊。结果筛查人群年龄、体重呈正态分布,不同孕周筛查人群的年龄构成和孕次构成无统计学意义;体重随着孕周的增加而增加。孕周与唐氏生筛查的假阳性率有相关性,16-18+6孕周段假阳性率低于其他孕周段。结论筛查年龄、体重和孕次分布对筛查效率无明显影响,筛查最佳孕周段为16-18+6周。
OBJECTIVE: To analyze the distribution of age, weight, pregnancy times and other factors in Down Syndrome screening population of each gestation week in the region and to analyze the relationship between gestational age and prenatal screening efficiency in order to find out more efficient screening gestational weeks in this region or Gestational period. Methods A retrospective analysis of 5,179 pregnant women in our hospital from 16 to 20 + 6 weeks prenatal screening of pregnant women triple serum markers for screening of pregnant women with high risk of Down Syndrome line amniotic fluid cell chromosome diagnosis. Results The age and body weight of the screening population showed a normal distribution. There was no significant difference in age composition and gestational age among the screening population at different gestational ages. Body weight increased with gestational age. Pregnancy and Down’s screening of false positive rate has a correlation, 16-18 +6 gestational week false positive rate lower than other gestational weeks. Conclusion The screening age, weight and distribution of pregnant women have no significant effect on the screening efficiency. The optimal gestational period of screening is 16-18 + 6 weeks.