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目的探讨米氮平合并匹维溴铵治疗肠易激综合征疗效。方法选择2009年5月到2010年12月在我院进行治疗的肠易激综合征患者68例作为研究对象,分为研究组和对照组,治疗效果采用汉米尔顿量表(HAMD)评分分析。结果统计分析表明HAMD评分研究组和对照组治疗前后比较均存在统计学意义(P<0.05),均为治疗后HAMD评分低于治疗前HAMD评分,治疗后研究组和治疗后对照组HAMD评分比较有统计学意义(P<0.05)。结论采用米氮平合并匹维溴铵治疗肠易激综合征疗效相对于单独使用米氮平有着较好的治疗效果,应加强推广。
Objective To investigate the efficacy of mirtazapine combined with pinaverium bromide in the treatment of irritable bowel syndrome. Methods Sixty-eight patients with irritable bowel syndrome who were treated in our hospital from May 2009 to December 2010 were selected as the study group and the control group. The therapeutic effect was evaluated by Hamilton’s scale (HAMD) . Results Statistical analysis showed that HAMD score was significantly higher in study group and control group before and after treatment (P <0.05), both HAMD score was lower than before treatment, HAMD score was higher in study group and post-treatment control group There was statistical significance (P <0.05). Conclusion Mirtazapine combined with pinaverium bromide in the treatment of irritable bowel syndrome has a better therapeutic effect than mirtazapine alone, and should be further promoted.