纽约市卫生局防痨科从1953年到1955年,曾研究了结核菌对链霉素和異菸肼发生耐药性的频度。为此曾检查898名患者,其中610名是新发现的活动性肺结核病患者,其余288名是结核病变增剧的患者,但此288人是从未用过抗菌剂治疗的。进行培养时,有385名患者(43％)的结核菌生长,其中43名(11％)是在含药培养基上生长的。新发现的病人的耐药性菌的出现略多于增剧型结核病人。例如,从新发现的肺结核病且在培养时有 From 1953 to 1955, the New York City Department of Health Prevention Division studied the frequency of TB resistance to streptomycin and isoniazid. To this end, 898 patients were examined, of which 610 were newly diagnosed active tuberculosis and the remaining 288 were those with tuberculosis. However, these 288 were never treated with antibacterials. In the culture, 385 patients (43%) grew M. tuberculosis, of whom 43 (11%) grew on drug-containing media. Newly discovered patients developed more resistant bacteria than those with exacerbated tuberculosis. For example, newly discovered pulmonary tuberculosis and when there is culture