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目的评价肱-踝脉搏波传导速度(ba-PWV)、踝臂指数(ABI)、颈动脉内中膜厚度(IMT)与冠心病冠状动脉狭窄严重程度之间的相关性。方法收集冠心病及可疑冠心病患者167例,结合冠状动脉造影结果,分析ba-PWV、IMT、ABI与冠脉狭窄程度的相关性。结果 ABII、MT、ba-PWV 3个检测指标单一应用时,冠脉单支病变组与非冠心病组相比无显著性差异,双支和多支病变组与非冠心病组相比有显著差异(P<0.01);当ABI、IMT、ba-PWV均异常或任意2个指标为异常与非冠心病组相比,单支病变组亦有显著性差异。结论 ba-PWV、ABI、IMT与冠状动脉病变狭窄程度具有明显相关性。联合应用ba-PWV、ABI和IMT,可用于评价冠状动脉粥样硬化性心脏病的严重程度。
Objective To evaluate the relationship between brachial-ankle pulse wave velocity (ba-PWV), ankle-brachial index (ABI), carotid intima-media thickness (IMT) and the severity of coronary artery stenosis. Methods 167 patients with coronary heart disease and suspected coronary heart disease were collected. The correlation between ba-PWV, IMT, ABI and severity of coronary artery stenosis was analyzed by coronary angiography. Results There was no significant difference between the single coronary artery disease group and the non-coronary heart disease group when the three indexes of ABII, MT and ba-PWV were applied singly, and there was significant difference between the double-branch and multi-vessel disease group and the non-coronary heart disease group (P <0.01). There was also a significant difference between the single-vessel lesion group and the non-coronary lesion group when the ABI, IMT, ba-PWV were abnormal or any two indexes were abnormal. Conclusion ba-PWV, ABI, IMT and coronary artery stenosis has a significant correlation. The combination of ba-PWV, ABI, and IMT can be used to assess the severity of coronary atherosclerotic heart disease.