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本文先回顾了过去用于溶解胆石的药物如乙醚、氯仿、肝素、消胆胺、苯巴比妥、安妥明、胆酸、猪脱氧胆酸等,但均因效果不佳而已停用,然后对目前认为最有效的药物鹅脱氧胆酸(Chenodeoxycbolicacid,下简称CDCA)作了综合介绍。近年有许多文献均认为CDCA对溶解胆固醇性胆石有效。文中引述某作者应用CDCA,同时以胆酸及安慰剂为对照,治疗上述患者,经服药6个月后,CDCA组18例中11例有效,而对照组则均无效。据已
This review first reviewed the drugs used to dissolve gallstones such as diethyl ether, chloroform, heparin, cholestyramine, phenobarbital, clofibrate, cholic acid, hyodeoxycholic acid, etc., but were disabled due to poor performance, and then At present, the most effective drug chenodeoxycholic acid (CDCA) was introduced. In recent years there are many literature that CDCA is effective in dissolving cholesterol gallstones. The article quoted an author using CDCA, while taking bile acid and placebo as controls, the treatment of these patients, after 6 months of medication, 18 cases of CDCA group of 11 cases effective, while the control group were ineffective. According to already