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本文报道了一条简便合成烯酰胺类化合物的方法。在酸酐或酰氯的存在下,通过钛锌试剂还原硝基芳基乙烯类化合物一步生成芳基烯酰胺类化合物,并利用此法实现了天然产物Alatamide的合成。
This article reports a simple method for the synthesis of enamide compounds. In the presence of acid anhydride or acid chloride, the nitroaryl ethers were reduced to form arylalkenylamides through titanium-zinc reagent in one step, and the synthesis of natural product Alatamide was realized by this method.