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目的观察布地奈德联合沙丁胺醇、异丙托溴铵雾化吸入治疗新生儿肺炎的临床疗效。方法选取医院2013年7月-2016年7月收治的新生儿肺炎患儿52例,随机分为试验组与对照组,每组26例。对照组采用常规治疗,试验组在对照组治疗的基础上给予布地奈德联合沙丁胺醇、异丙托溴铵雾化吸入治疗。比较2组患儿临床疗效、症状消失时间、血气分析。结果试验组总有效率为100.00%明显高于对照组的76.92%,差异有统计学意义(P<0.05)。试验组症状消失时间明显短于对照组,差异有统计学意义(P<0.05)。治疗前2组患儿血气分析比较差异无统计学意义(P>0.05),治疗后2组血气分析均改善,且试验组明显优于对照组,差异均有统计学意义(P<0.05)。结论布地奈德联合沙丁胺醇、异丙托溴铵雾化吸入治疗新生儿肺炎疗效显著,值得临床推广使用。
Objective To observe the clinical efficacy of budesonide combined with salbutamol and ipratropium bromide inhalation in the treatment of neonatal pneumonia. Methods Fifty-two children with neonatal pneumonia admitted from July 2013 to July 2016 in our hospital were randomly divided into experimental group and control group, with 26 cases in each group. The control group was treated with conventional therapy. The experimental group was treated with budesonide combined with salbutamol and ipratropium bromide inhalation on the basis of the control group. The clinical efficacy, symptom disappear time, blood gas analysis in two groups were compared. Results The total effective rate was 100.00% in the experimental group was significantly higher than 76.92% in the control group, the difference was statistically significant (P <0.05). The symptom disappearance time of the experimental group was significantly shorter than that of the control group, the difference was statistically significant (P <0.05). There was no significant difference in blood gas analysis between the two groups before treatment (P> 0.05). The blood gas analysis in both groups improved after treatment, and the experimental group was significantly better than the control group (P <0.05). Conclusion Budesonide combined with salbutamol, ipratropium bromide inhalation treatment of neonatal pneumonia, significant effect, worthy of clinical promotion.