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应用２４ ｈ 动态心电图观察了尼莫地平（ｎｉｍｏｄｉｐｉｎｅ） 对大鼠脑出血后室性心律失常的防治作用及对脑水质量分数的影响。结果：对照组、脑出血组和脑出血＋ 尼莫地平治疗组３ 组大鼠的室性早搏分别为（０ ．３ ±０ ．５） 万个／ｄ 、（１ ．４ ±１ ．６） 万个／ｄ 和（０ ．７ ±０ ．７） 万个／ｄ ，尼莫地平治疗组与对照组比较无显著性差异（ Ｐ＞ ０ ．０５） ，上述２ 组与脑出血组比较有显著性差异（ Ｐ＜ ０ ．０５ 、 Ｐ＜ ０ ．０１） 。脑出血组、尼莫地平治疗组脑水质量分数分别为（８１ ．０４ ±０ ．４６） ％ 和（８０ ．６０ ±０ ．５８） ％ ，２ 组比较有显著性差异（ Ｐ＜ ０ ．０５） 。说明尼莫地平可减少大鼠脑出血后室性心律失常的发生，明显降低脑水质量分数。
The effect of nimodipine on the prevention and treatment of ventricular arrhythmia after intracerebral hemorrhage and its effect on cerebral water quality score were observed by 24 h Holter monitoring. Results: The ventricular premature beats in the control, intracerebral hemorrhage and intracerebral hemorrhage + nimodipine groups were (0.3 ± 0.5) million / d, (1.4 ± 1.6) There was no significant difference between the nimodipine treatment group and the control group (P> 0.05). There was significant difference between the above two groups and the cerebral hemorrhage group Sex differences (P <0.05, P <0.01). Cerebral hemorrhage group and nimodipine treatment group were (81 .04 ± 0.46)% and (80.60 ± 0.58)%, respectively. There were significant differences between the two groups (P <0.05) ). Nimodipine can reduce the incidence of ventricular arrhythmia after cerebral hemorrhage in rats, significantly reduce the water quality score.