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硒是人体必需微量元素,有着广泛的生物学效应。硒与多种疾病的发生有关。硒及其化合物与肿瘤的关系研究最多。大部分研究结果表明硒具有防癌、抗癌功能。但是,硒对于不同肿瘤的作用效果和机制却不尽相同。由于硒在体内代谢复杂,其防癌、抗癌机制的研究也较为困难。该文就硒及其化合物对不同肿瘤的作用效果和机制研究现状进行综述,并对今后有关低硒与肿瘤的因果关系以及防治肿瘤所需硒补充剂量的相关研究工作进行展望。
Selenium is an essential trace element of the human body and has a wide range of biological effects. Selenium and a variety of diseases related. Selenium and its compounds and tumor most studied. Most of the results show that selenium has anti-cancer, anti-cancer function. However, the effect and mechanism of selenium on different tumors are not the same. Due to the complex metabolism of selenium in the body, its anti-cancer and anti-cancer mechanisms are also more difficult to study. This article reviewed the research progress of the effect and mechanism of selenium and its compounds on different tumors, and looked forward to the future research about the causal relationship between selenium and tumor and the dose of selenium needed to prevent and treat the tumor.