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眼眶炎性假瘤系原发于眼眶组织的慢性非特异性炎症改变。病因不明,有感染和免疫功能紊乱等假说。临床上主要表现为突眼、眶内肿块、可伴有眼痛、睑结膜充血水肿等炎症症状和体征。超声扫描和CT检查常显示眼外肌变粗、视神经变粗和眶内软组织肿块影象。若出现Tenon氏囊加宽和眼环增厚,则提示病变多系炎症性改变,具有鉴别诊断的参考价值。炎性假瘤病理学改变呈现不同程度的炎性和细胞浸润、增殖伴有纤维结缔组织增生,其特征是细胞成分的多形性和成熟性。本文对炎性假瘤的鉴别诊断以及皮质激素、外科手术、放射治疗的适应证和疗效作了总结,并对其预后作了评价。
Orbital inflammatory pseudotumor primary orbital tissue in the chronic non-specific inflammatory changes. Etiology is unknown, there are infections and immune dysfunction hypothesis. The main clinical manifestations of exophthalmos, orbital mass, may be associated with eye pain, conjunctival congestion and edema and other inflammatory symptoms and signs. Ultrasound and CT examination often showed extraocular muscle thickening, optic nerve thickening and orbital soft tissue mass image. If there is widening Tenon’s capsule and eye ring thickening, suggesting that multiple lesions of inflammatory changes, with a differential diagnosis of reference value. Inflammatory pseudotumor pathological changes showed varying degrees of inflammation and cell infiltration, proliferation accompanied by fibrous connective tissue proliferation, which is characterized by cellular components of the polymorphism and maturation. In this paper, the differential diagnosis of inflammatory pseudotumor and corticosteroids, surgery, radiotherapy indications and efficacy were summarized, and its prognosis was evaluated.