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目的观察慢性肾功能衰竭(CRF)采用血液透析治疗的临床效果。方法 2011年2月-2014年2月医院肾内科收治慢性肾功能衰竭患者68例,均给予血液透析治疗,4h/次,3次/周。3个月为1个疗程。1个疗程后,测定患者治疗前后尿素氮(BUN)、血肌酐(Scr)、血钾、血脂[胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)]的变化。结果透析后BUN、Scr、血钾、血脂(TC、TG、LDL-C、HDL-C)均较透析前降低,差异有统计学意义(P<0.05)。透析过程中发生低血压7例(10.3%),消化道出血4例(5.9%),均经对症处理后缓解。死亡10例(14.7%)。结论采用血液透析治疗能明显改善CRF患者肾功能,提高生存质量。但注意对透析并发症如低血压症的预防处理。
Objective To observe the clinical effect of hemodialysis on chronic renal failure (CRF). Methods From February 2011 to February 2014, 68 patients with chronic renal failure admitted to Department of Nephrology of Hospitals were treated with hemodialysis for 4h, 3 times a week. 3 months for a course of treatment. After 1 course of treatment, the blood urea nitrogen (BUN), serum creatinine (Scr), serum potassium, blood lipid [TC, triglyceride (TG), low density lipoprotein cholesterol (LDL- Density lipoprotein cholesterol (HDL-C)] changes. Results The levels of BUN, Scr, serum potassium, serum lipids (TC, TG, LDL-C and HDL-C) in dialysis group were significantly lower than those before dialysis (P <0.05). Dialysis process occurred in 7 cases of hypotension (10.3%), gastrointestinal bleeding in 4 cases (5.9%), were relieved after symptomatic treatment. Ten patients died (14.7%). Conclusion Hemodialysis can significantly improve renal function and improve quality of life in patients with CRF. But pay attention to dialysis complications such as prevention and treatment of hypotension.