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目的:了解高渗氯化钠羟乙基淀粉40小容量复苏在低血容量休克及猝死患者CPR抢救中的临床效果。方法:将低血容量休克及猝死患者CPR分为常规治疗组(对照组)及高渗氯化钠羟乙基淀粉40治疗组,并观察治疗后30、60、90min血压达标(≥65mmHg)人数进行对比分析。结果:低血容量休克患者两组比较:30、60min有统计学差异(P<0.001),而90min及90min以后无统计学差异(P>0.05),两组综合比较有统计学差异(P<0.05)。猝死患者两组比较:30min时两组对比无统计学差异(P>0.05),在60、90min时两组分别统计对比有统计学差异(P60′<0.001,P90′<0.05)。结论:在低血容量休克及猝死患者临床抢救中应用高渗氯化钠羟乙基淀粉40小容量复苏方法简便,能在较短时间内恢复有效的循环量,缩短由于低血容量导致的组织器官血液灌注时间,阻断可能发生的后续多器官损害,为专科抢救效果奠定基础。
Objective: To investigate the clinical effect of hypertonic sodium chloride hydroxyethyl starch 40 small volume resuscitation in the rescue of CPR in patients with hypovolemic shock and sudden death. Methods: The CPR of patients with hypovolemic shock and sudden death were divided into routine treatment group (control group) and hypertonic sodium chloride hydroxyethyl starch 40 treatment group, and the blood pressure standard (≥65mmHg) For comparative analysis. Results: There was a significant difference between the two groups at 30 and 60 minutes (P <0.001), but no significant difference at 90 and 90 minutes (P> 0.05). There was a significant difference between the two groups (P < 0.05). There was no significant difference between the two groups at 30 minutes (P> 0.05). There was significant difference between the two groups at 60 and 90 minutes (P60 ’<0.001, P90’ <0.05). Conclusion: It is simple and convenient to use hypertonic sodium chloride hydroxyethyl starch 40 small volume resuscitation in the rescue of patients with hypovolemic shock and sudden death, which can restore effective circulation volume and shorten the period of low blood volume induced tissue Organ blood perfusion time, blocking the subsequent occurrence of multiple organ damage may be the basis for the specialist rescue effect.