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多囊卵巢综合征(polycystic ovary syndrome,PCOS)是常见的代谢异常和激素分泌紊乱的异质性疾病,在适孕女性的不孕不育症中占6%~8%[1]。高雄激素在PCOS形成中起着重要作用,而胰岛素抵抗和糖耐量异常是PCOS最为重要的表现之一,大约70%的PCOS患者存在胰岛素抵抗[2],这是导致PCOS发展成为2型糖尿病、增加心血管疾病危险的重要因素。胰岛素抵抗越来越引起人们的注意,我们于2012年4月至2013年3月探讨高雄激素血症和胰岛素抵抗是否存在联系,报告如下。材料与方法1.实验动物:C57BL/6J野生型雌性小鼠(华阜
Polycystic ovary syndrome (PCOS) is a common heterogeneity of metabolic disorders and hormone disorders, accounting for 6% to 8% of infertility infertile women [1]. Kaohsiung and Hormone play an important role in the formation of PCOS. Insulin resistance and impaired glucose tolerance are one of the most important manifestations of PCOS. Insulin resistance is present in about 70% of PCOS patients [2], which leads to the development of PCOS into type 2 diabetes, An important factor that increases the risk of cardiovascular disease. Insulin resistance is attracting more and more attention. From April 2012 to March 2013, we explored whether there is a link between hyperandrogenism and insulin resistance. The report is as follows. Materials and Methods 1. Experimental animals: C57BL / 6J wild-type female mice (Hua Fu