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目的观察母亲在分娩过程中应用缩宫素与新生儿黄疸的关系。方法对400例正常出生的单胎足月新生儿进行分组对照分析,观察缩宫素对新生儿胆红素代谢的影响。母亲分娩过程中曾应用缩宫素221例,未曾应用缩宫素179例,观察两组病例的血清胆红素均值及新生儿高胆红素血症的发病率。结果用药组血清胆红素均值大于未用药组,差异有统计学意义(P<0.05);用药组高胆红素血症的发病率比未用药组高,差异有统计学意义(P<0.05)。结论与对照组组比较,血清胆红素均值及新生儿高胆红素血症的发病率均较高,母亲在分娩过程中应用缩宫素与新生儿高胆红素血症的发病有密切关系。
Objective To observe the relationship between mothers applying oxytocin and neonatal jaundice during childbirth. Methods 400 cases of singleton full-term newborn babies were analyzed by grouping to observe the effect of oxytocin on neonatal bilirubin metabolism. 221 cases of oxytocin had been applied during delivery in mother and 179 cases of oxytocin had not been applied. The mean serum bilirubin and the incidence of neonatal hyperbilirubinemia were observed in both groups. Results The average serum bilirubin value in the treatment group was significantly higher than that in the untreated group (P <0.05). The incidence of hyperbilirubinemia in the treatment group was significantly higher than that in the untreated group (P <0.05) ). Conclusion Compared with the control group, the mean serum bilirubin and the incidence of neonatal hyperbilirubinemia were high. The mothers who applied oxytocin during labor were closely associated with the incidence of neonatal hyperbilirubinemia relationship.