为研究与β_2微球蛋白(β_2—M)产生强相互作用的高分子配位体,作者通过计算机图解(C.G)绘制出人类β—M的二维结构,并用新改进的酶标免疫测定法(EIAP法)评价来自C.G的高分子配位体的假设。结果表明,C.G表示出在β_2—M分子表面有三个区域,第一个区域富含疏水氨基酸残基,第二个区域富含疏水及碱性氨基酸残基,第三个区域 In order to study the polymer ligands that strongly interact with β_2-microglobulin (β_2-M), the authors mapped the two-dimensional structure of human β-M by computer graphics (CG) (EIAP method) to evaluate the hypotheses of macromolecular ligands from CG. The results show that C.G shows that there are three regions on the surface of β_2-M molecule, the first region is rich in hydrophobic amino acid residues, the second region is rich in hydrophobic and basic amino acid residues, the third region