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目的 本文报道我院自1971～1988年收治的10例原发睾丸的胚胎性横纹肌肉瘤.全部病例均经术后病理证实,均为睾丸切除术后再行后腹膜淋巴结清扫.3例后腹膜淋巴结阴性.方法 全组中2例接受术后放疗,7例接受辅助化疗.结果 二年和五年生存率分别为50%和30%.结论 由于原发睾丸的胚胎性横纹肌肉瘤少见,本文结合文献报道探讨其疗效及影响预后的因素.本病的治疗为手术结合化疗和放疗,加强化疗可能提高疗效.本病成人预后较儿童差,后腹膜淋巴结转移也是影响预后的因素.在睾丸切除术后如CT等影像学诊断阴性,可不必行后腹膜淋巴结清扫术.
Objective To report 10 cases of primary rhabdomyosarcoma of the primary testes treated in our hospital from 1971 to 1988. All cases were confirmed by postoperative pathology and all were retroperitoneal lymph node dissections after orchiectomy. Three cases had peritoneal lymph nodes. Negative. Methods In the whole group, 2 patients received postoperative radiotherapy and 7 patients received adjuvant chemotherapy. The results of the two-year and five-year survival rates were 50% and 30%, respectively. Conclusions Embryonic rhabdomyosarcoma of the primary testis is rare. The report discusses its efficacy and factors that affect prognosis. The treatment of the disease is surgery combined with chemotherapy and radiotherapy. Strengthening chemotherapy may improve the efficacy. The prognosis of this disease is poorer than that of children. Retroperitoneal lymph node metastasis is also a factor that influences prognosis. After orchiectomy Such as CT and other negative diagnostic imaging, can not be retroperitoneal lymph node dissection.