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目的:探讨铱192放射治疗结合腔内手术治疗短段前尿道狭窄,降低腔内手术术后复发率。方法:短段前尿道狭窄患者286例,均行尿道内切开术,再将其随机分为两组,一组为173例,术后尽早行狭窄段铱192放射治疗;另一组为113例,未行放疗。术后随访1年,比较两组之间的复发率(x~2检验)。结果:286例均手术成功,放疗组1年内19例复发,复发率为10.98%;未放疗组1年内62例复发,复发率为54.86%。两组之间比较差异有统计学意义(P=0.003)。结论:腔内手术治疗短段前尿道狭窄术后尽早行狭窄段铱192放射治疗是预防狭窄术后复发的有效手段。
Objective: To investigate the treatment of short anterior urethral stricture by iridium 192 combined with intracavitary surgery and to reduce the postoperative recurrence rate of intracavitary surgery. Methods: A total of 286 patients with short anterior urethral stricture underwent endotracheal incision. The patients were divided into two groups at random. One group was 173 cases. The other group was 113 For example, no radiotherapy. The patients were followed up for 1 year. The recurrence rate (x ~ 2 test) was compared between the two groups. Results: All of the 286 cases were operated successfully. In the radiotherapy group, 19 cases relapsed within one year, the recurrence rate was 10.98%. In the non-radiotherapy group, 62 cases relapsed within one year, the recurrence rate was 54.86%. The difference between the two groups was statistically significant (P = 0.003). CONCLUSIONS: Endovascular treatment of short-term anterior urethral stricture as soon as possible after stenosis iridium 192 radiation therapy is an effective means to prevent recurrence of stenosis.