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以胎儿脐带血ｐＨ值为指标评价羊水胎粪污染，预测妊娠胆汁瘀积症（ＩＣＰ）患者围产儿结局的敏感性。结果：ＩＣＰ组ｐＨ＜７．２者１０例，８例羊水胎粪污染，阳性预测值为８０．０％，ｐＨ≥７．２者２０例，羊水胎粪污染４例，阴性预测值为８０．０％；对照组ｐＨ＜７．２者５例，羊水胎粪污染３例，阳性预测值６０．０％，ｐＨ≥７．２者２５例，羊水胎粪污染２例，阴性预测值９８．０％。两组间阳性预测值和阴性预测值均无统计学差异（Ｐ＞０．０５），但两组的阳性预测值和阴性预测值都比较高，表明羊水胎粪污染与胎儿宫内缺氧密切相关。而且，ＩＣＰ组羊水胎粪污染的发生率（４０．０％）明显高于对照组（１６．７％，Ｐ＜０．０５）。因此，我们主张对于ＩＣＰ患者，在妊娠期和分娩期应特别注意观察羊水有无胎粪污染。
The fetal umbilical cord blood pH value as an indicator of amniotic fluid meconium contamination, prediction of pregnancy cholestasis (ICP) perinatal outcome of patients with sensitivity. Results: The ICP group had pH <7.2 in 10 cases, 8 cases of amniotic fluid meconium contamination, the positive predictive value was 80.0%, pH ≥ 7.2 in 20 cases, amniotic fluid meconium contamination in 4 cases, the negative predictive value of 80 .0%; control group pH <7.2 in 5 cases, amniotic fluid meconium in 3 cases, the positive predictive value of 60.0%, pH≥7.2 in 25 cases, amniotic fluid meconium staining in 2 cases, the negative predictive value of 98 .0%. There was no significant difference between the two groups in the positive predictive value and negative predictive value (P> 0.05), but the positive predictive value and negative predictive value were higher in both groups, indicating that meconium-stained amniotic fluid is closely related to fetal hypoxia Related. Moreover, the incidence of meconium-stained amniotic fluid in the ICP group (40.0%) was significantly higher than that in the control group (16.7%, P <0.05). Therefore, we advocate that for ICP patients, special attention should be paid during pregnancy and childbirth observation of meconium amniotic fluid contamination.