检测循环免疫复合物(CIC)对于自身免疫性疾病发病机理的研究有着重要价值。由于CIC复杂的免疫生物学活性和理化性状,基于不同原理而建立的检测方法甚多,但适用范围多较局限,测定结果也常相距甚远。为了选择一种适于常规应用的敏感、简便、可靠的CIC检测方法,我们对三种CIC测定方法进行了比较研究,现将结果报告如下。 Detection of circulating immune complexes (CIC) is of great value in the study of the pathogenesis of autoimmune diseases. Due to the complex immunological biological activity and physicochemical properties of CIC, there are many detection methods based on different principles, but the applicable scope is more limited and the determination results are often far apart. In order to choose a sensitive, simple and reliable CIC detection method suitable for routine applications, we compared the three CIC measurement methods and the results are reported as follows.