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目的探讨甲硝唑对雄激素合成和分泌的影响。方法采用透射电镜、酶组织化学定量及放射免疫测定技术进行研究。结果间质细胞超微结构、睾酮的合成和分泌均无异常。结论甲硝唑不影响间质细胞组织结构及睾酮的合成与分泌。
Objective To investigate the effect of metronidazole on the synthesis and secretion of androgen. Methods Transmission electron microscopy, enzymatic histochemical quantification and radioimmunoassay techniques were studied. Results There was no abnormality in the ultrastructure of stromal cells and the synthesis and secretion of testosterone. Conclusion Metronidazole does not affect the stromal cell structure and testosterone synthesis and secretion.