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An efficient and eco-friendly method is reported for the synthesis of 2-substituted-2,3-dihydroquinazolin -4(1 H)-ones from direct cyclocondensation of anthranilamide with aldehydes and ketones using N-propylsulfamic acid supported onto magnetic Fe_3O_4 nanoparticles(MNPs-PSA) as a recoverable and recyclable nanocatalyst in good to excellent yields in water at 70℃.The catalyst was readily separated using an external magnet and reusable without significant loss of their catalytic efficiency.
An efficient and eco-friendly method is reported for the synthesis of 2-substituted-2,3-dihydroquinazolin-4 (1H) -ones from direct cyclocondensation of anthranilamide with aldehydes and ketones using N-propylsulfamic acid supported on magnetic Fe_3O_4 nanoparticles MNPs-PSA) as a recoverable and recyclable nanocatalyst in good to excellent yields in water at 70 ° C. The catalyst was readily separated using an external magnet and reusable without significant loss of their catalytic efficiency.