患者男,40岁,因发现巩膜、皮肤黄染10余天入院。患者10余天前发现巩膜及全身皮肤黄染,并逐渐加重,无明显食欲不振,无皮肤瘙痒,无厌油、恶心、呕吐,无腹痛、腹胀,无全身乏力,无口鼻黏膜出血,小便颜色深黄色。患者既往有吸烟史20余年,每日约30支,有饮酒史15年,每日饮酒折合酒精量约150 g。无肝炎病史及其密切接触史,无输血史,无用药史,无药物及食物过敏史。否认有毒物质接 Male patient, 40 years old, because of the discovery of the sclera, yellow skin dye more than 10 days admitted. More than 10 days before the discovery of the sclera and body skin yellow dye, and gradually increased, no obvious loss of appetite, no skin itching, no greasy oil, nausea, vomiting, no abdominal pain, bloating, no generalized weakness, no mucosal bleeding, no urine Dark yellow. Past history of patients with smoking more than 20 years, about 30 daily, a history of drinking 15 years, equivalent to about 150 grams of alcohol per day. No history of hepatitis and its close contact history, no blood transfusion history, no medication history, no drug and food allergy history. Denied the connection of toxic substances