论文部分内容阅读
目的分析瘢痕子宫再次剖宫产围术期不同预防用药方式对术后感染的影响,以期促进临床合理使用抗菌药物。方法回顾性分析2009年1月-2014年5月该院202例瘢痕子宫再次行剖宫产围术期预防使用抗菌药物的方式及术后感染情况。以2011年5月-2014年5月在该院实施剖宫产的瘢痕子宫患者108例为观察组,使用头孢唑啉钠术中断脐后用药,术后24h停药;以2009年1月-2011年4月在该院实施剖宫产的瘢痕子宫患者94例为对照组,使用头孢噻肟钠术前30 min用药,术后48 h停药。比较两组术后感染情况。结果两组手术部位感染、产褥病率、术后退热时间比较,差异均无统计学意义(P>0.05)。结论在无其他合并症及感染高危因素的瘢痕子宫择期手术围术期预防性使用抗菌药物,建议严格遵循《剖宫产手术围手术期预防用抗菌药物管理实施细则》(征求意见稿)推荐用药方式,减轻患者经济负担,减少头孢二代、三代抗菌药物使用量从而降低此类药物的耐药性。
Objective To analyze the effect of different prophylaxis modes of cesarean section during cesarean section on postoperative infection in order to promote the rational use of antimicrobial agents. Methods From January 2009 to May 2014, 202 patients with scarred uterus in our hospital were retrospectively analyzed about the prophylactic use of antibacterials and their postoperative infection during cesarean section. From May 2011 to May 2014, 108 cases of scarring uterus under cesarean section were treated in this hospital. The patients in observation group were treated with cefazolin sodium and the drug was discontinued after 24 hours. In April 2011, 94 patients with cesarean scar were treated with cefotaxime sodium 30 min before operation and 48 h after operation. Postoperative infection was compared between the two groups. Results There were no significant differences in the infection of surgical site, the rate of puerperal obstruction and the time of postoperative fever (P> 0.05). Conclusions In the perioperative period of prophylactic use of elective surgical treatment of scarring uterus without other comorbidities and high risk factors, it is recommended to strictly follow the “Cesarean section perioperative implementation of antimicrobial prophylaxis management rules” (Draft) recommended drugs Way to reduce the financial burden on patients and reduce the use of second generation and third generation antibacterial drugs to reduce the drug resistance of these drugs.