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[目的]测试人工寰椎齿状突关节置换后寰枢椎的稳定性和功能,并与Magerl经关节螺钉固定进行比较.[方法]将12例新鲜的成人头颈部标本随机分为两组,第1组在齿状突切除术后使用人工寰齿关节置换;第2组在齿状突切除术后使用Magerl经关节螺钉固定.对两组的每一标本分别测定完整状态、人工关节置换术后或经关节螺钉固定后的运动范围和中性区.[结果]人工关节置换术后与完整状态相比前屈、后伸、左右侧屈的运动范围和中性区明显减小(P<0.05),左右旋转的运动范围无显著差异(P>0.05),中性区增大(P<0.05).Maged经关节螺钉固定后与完整状态相比前屈、后伸、左右侧屈及左右旋转的运动范围和中性区均明显减小(P<0.05).人工关节置换术后及Magerl经关节螺钉固定后两组在前屈、后伸及左右侧屈的ROM稳定指数和NZ稳定指数相比均无显著差异(P>0.05).[结论]实验证实在齿状突切除后,进行自行设计的人工寰椎齿状突关节置换可取得与Magerl经关节螺钉固定相似的前屈、后伸及左右侧屈稳定性,重要的是与完整状态相比左右旋转的运动范围无显著差异,最大限度的保留了寰枢复合体重要的旋转功能,对以往齿状突切除、脊髓减压后需要使用寰枢椎融合的患者,提供了另一种术式的选择.“,”[Objective]To determine the initial stability and function of a new artificial joint in a cadaveric cervical spine model by comparing it with a conventional method.[Methods]Twelve fresh human cadaveric cervical spines(C_(0~3))were randomly divided into 2 groups:group 1,resection of the odontoid with artificial atlanto-odontoid joint(AAOJ),and group 2,resection of the odontoid with Magerl atlas and axis by transarticular screw fixation(Magerl).For each specimen,the intact and resection of the odontoid underwent a flexibility test firstly,followed by the instrumented construct Rotational angles of the C_(0~3) segment were measured to study the immediate stability and function of resection of the odontoid and AAOJ,compared with the intact and resection of the odontoid and Magerl.[Results]Compared to the intact state,resection of the odontoid and AAOJ resulted in a significant decrease in the range of motion(ROM)and neutral zone(NZ)during flexion,extension,and lateral bending(P<0.05);however,with regard to axial rotation,there was no significant difference in ROM(P>0.05).Compared to the intact state,resection of the odontoid and Magerl resulted in a significant decrease in the range of motion(ROM)and neutral zone(NZ)during all 6 degrees of freedom(P<0.05).Compared with resection of the odontoid and Magerl,resection of the odontoid and AAOJ during flexion,extension,and lateral bending,showed no significant difference in ROM(P>0.05).[Conclusion]A new type of artificial atlanto-odontoid joint has been designed for correcting atlantoaxial instability resulted from C_(1、2) anterior decompression procedures.It can restore,to a great extent,the C_(1、2) axial rotation that is lost during current stabilization procedures.