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目的探讨不同剂量布地奈德混悬液雾化吸入治疗小儿急性哮喘的疗效。方法选择2011年3月至2013年4月急性哮喘患儿58例,随机分为两组,每组各29例。两组患儿全部给予口服2 mg/kg泼尼松,雾化吸入1~2 mg硫酸沙丁胺醇。在此基础上,对照组吸入0.5 mg布地奈德混悬液,观察组吸入1.0 mg布地奈德混悬液。比较两组疗效。结果观察组临床症状的改善程度、症状消失时间、PEF占预计值百分比均优于对照组,差异有统计学意义(P<0.05)。结论大剂量布地奈德混悬液雾化吸入可有效治疗小儿哮喘急性发作,控制住院时间,提高安全性,值得临床推广。
Objective To investigate the efficacy of different doses of budesonide suspension atomization inhalation in children with acute asthma. Methods From March 2011 to April 2013, 58 children with acute asthma were randomly divided into two groups (n = 29 in each group). Two groups of children were given oral 2 mg / kg of prednisone, inhaled 1 to 2 mg of salbutamol sulfate. On this basis, the control group inhaled 0.5 mg budesonide suspension, the observation group inhaled 1.0 mg budesonide suspension. Compare the two groups curative effect. Results The improvement of clinical symptoms, the disappearance of symptoms and the percentage of predicted PEF in observation group were better than those in control group (P <0.05). Conclusion High-dose budesonide suspension inhalation can effectively treat children with acute asthma attacks, control hospital stay and improve safety, worthy of clinical promotion.