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卒中已成为中国成人的第一死因[1],每年新发卒中病例250万人[2]。心房颤动(房颤)是卒中发生的独立危险因素,房颤患者发生卒中的风险是普通人群的5倍[3]。近半个世纪以来,维生素K拮抗剂华法林一直是预防心源性卒中不可替代的重要治疗手段。但华法林在用药过程中需要频繁监
Stroke has become the leading cause of death among Chinese adults [1], with 2.5 million new strokes each year [2]. Atrial fibrillation (atrial fibrillation) is an independent risk factor for stroke, and the risk of stroke in atrial fibrillation is 5 times greater than in the general population [3]. For nearly half a century, warfarin, a vitamin K antagonist, has been an important and irreplaceable treatment for cardioembolic stroke. However, warfarin is frequently monitored in the course of medication