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目的探讨脑梗死患者颈动脉病变与眼底动脉硬化的相关性。方法选择脑梗死患者177例,分别进行头颅CT或MRI、颈动脉超声和眼底照相检查,评价颈动脉内膜中层厚度、颈动脉狭窄及眼底动脉硬化分级。结果177例患者中,颈动脉无病变10例(5.6%),颈总动脉内膜中层厚度增厚22例(12.4%),任意颈动脉斑块形成121例(68.4%),颈动脉狭窄24例(13.6%)。正常35例(19.8%),眼底动脉硬化改变142例(80.2%),其中Ⅰ级69例(39.0%),Ⅱ级31例(17.5%),Ⅲ级42例(23.7%)。眼底动脉硬化与颈动脉内膜中层厚度、颈动脉狭窄相关(P<0.05),但眼底动脉硬化各单项指标与颈动脉内膜中层厚度和颈动脉是否狭窄无相关性(P>0.05)。结论眼底动脉硬化与颈动脉病变存在一致性,眼底照相可作为辅助方法帮助评价全身血管情况,协助颈动脉疾病的诊断。
Objective To investigate the correlation between carotid artery lesions and retinal arteriosclerosis in patients with cerebral infarction. Methods One hundred and seventy-seven patients with cerebral infarction were selected and examined by cranial CT or MRI, carotid artery ultrasound and fundus photography. The carotid artery intima-media thickness, carotid artery stenosis and fundus arteriosclerosis were evaluated. Results Among the 177 patients, there were 10 cases (5.6%) with no carotid artery disease, 22 cases (12.4%) with common carotid artery intima-media thickness, 121 cases (68.4%) with any carotid artery plaque, Example (13.6%). There were 142 cases (80.2%) with arteriosclerosis of the fundus in 35 cases (19.8%) and 69 cases (39.0%). There were 31 cases (17.5%) in grade Ⅱ and 42 cases (23.7%) in grade Ⅲ. The fundus atherosclerosis was correlated with carotid artery intima-media thickness and carotid stenosis (P <0.05). However, there was no correlation between each index of atherosclerosis and carotid artery intima-media thickness and carotid artery stenosis (P> 0.05). Conclusions There is consistency between fundus arteriosclerosis and carotid artery disease. Fundus photography can be used as an auxiliary method to help assess the whole blood vessel condition and assist in the diagnosis of carotid artery disease.