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目的:探讨微信平台联合家庭参与在血脂异常人群健康管理中的应用。方法:选取2017年3至8月在重庆市人民医院健康管理中心体检结论为血脂异常的100例,采用自主报名的方式将其分为干预组和对照组,各50例。对照组进行常规健康指导及电话随访;干预组从2017年9月开始进行为期6个月的干预,实施以微信平台联合家庭参与的健康管理方式,即借助微信平台,通过家庭成员与医护共同参与的方式进行管理,由专业健康管理医护团队对其进行实时咨询、监测、随访、解答疑问等。采用n t检验比较2组人群的总胆固醇、三酰甘油、低密度脂蛋白胆固醇指标,采用χ2检验比较2组人群生活习惯的改善情况。n 结果:干预前2组人群各指标差异无统计学意义(n P>0.05)。干预6个月后,干预组空腹总胆固醇(6.18±0.93) mmol/L、低密度脂蛋白胆固醇(2.96±0.67) mmol/L、三酰甘油(2.20±0.35) mmol/L均分别低于对照组(7.17±1.07) mmol/L、(3.26±0.57) mmol/L、(2.41±0.36) mmol/L,差异有统计学意义(n P<0.05)。干预组干预后6个月不良生活习惯所占比例(饮食不规律18%、运动缺乏22%、失眠26%、吸烟14%、饮酒18%)均明显低于对照组(饮食不规律58%、运动缺乏74%、失眠54%、吸烟38%、饮酒42%),差异均有统计学意义(n P0.05). After 6 months of intervention, fasting total cholesterol (6.18±0.93) mmol/L, low-density lipoprotein cholesterol (2.96±0.67) mmol/L and triglyceride (2.20±0.35) mmol/L were all lower in the intervention group than in the control group (7.17±1.07) mmol/L, (3.26±0.57) mmol/L and (2.41±0.36) mmol/L, respectively, with statistically significant difference (n P<0.05). After 6 months of intervention, the proportion of people in the intervention group (18% irregular diet, 22% lack of exercise, 26% insomnia, 14% smoking and 18% drinking) was significantly lower than that in the control group (58% irregular diet, 74% lack of exercise, 54% insomnia, 38% smoking and 42% drinking), and the difference was statistically significant (n P<0.05).n Conclusions:Dyslipidemia is closely related to living habits. Through the help of the WeChat platform, family members and medical staff can participate together and effectively improve the living habits of people with dyslipidemia, so as to improve the indicators of lipid metabolism.