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多药耐药是乳腺癌化疗失败的关键。发掘、探索低毒、高效、多阶段性作用的中药是目前研究的热点。研究发现,补骨脂素对多药耐药具有一定的逆转作用,现就其逆转机制及其原理进行阐述。
Multidrug resistance is the key to the failure of chemotherapy in breast cancer. To explore and explore the low toxicity, high efficiency, multi-stage effect of traditional Chinese medicine is the current research hot spots. The study found that psoralen has some reversal effects on multidrug resistance, and now its reversal mechanism and its principle are described.