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恶性肿瘤患者的胸腹水,由于癌细胞的多态性和间皮细胞的良性反应,造成了细胞学诊断上的困难,但可根据癌性体腔积液中有较多的癌细胞核分裂相,在临床上应用染色体分析帮助诊断。我们在1982年3月至1983年8月,采取双盲法将染色体分析与龙溪地区医院病理科胸腹水脱落细胞检查(下称细胞学检查)结果作比较,并与病理等检查及随访结果对照,对154例未经抗癌治疗的住院患者胸腹水进行染色体分析,一般能在2~3小时内对癌性胸腹水单独作出诊断,现报告于下。
Malignant tumor patients with pleural effusion and ascites, due to cancer cell polymorphisms and mesothelial cell benign reactions, caused cytological diagnosis difficulties, but according to the cancerous body effusion, there are more cancer cell mitotic phases, Chromosomal analysis is used clinically to help diagnose. From March 1982 to August 1983, we performed a double-blind method to compare chromosomal analysis with the results of pleural and peritoneal fluid exfoliative cell examination (hereinafter referred to as cytological examination) in Longxi District Hospital Pathology Department, and compared the findings with pathological examinations and follow-up results. In contrast, chromosomal analysis was performed on thoracic and ascitic fluid in 154 hospitalized patients who had not been treated for anti-cancer therapy. The diagnosis of cancerous pleural effusion and ascites was generally made within 2 to 3 hours and is reported below.