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目的观察高聚金葡素灌注膀胱预防膀胱移行细胞癌复发的疗效。方法对保留膀胱手术治疗217例中的43例膀胱移行细胞癌患者术后采用高聚金葡素行膀胱灌注治疗,并与同期其他药物灌注治疗进行比较。结果43例全部随访,随访时间3～30个月,平均随访期15个月,复发8例,复发率为18.6%,与同期内其他药物灌注的预防效果差异无统计学意义,并发症和不良反应小。结论高聚金葡素是一种有效预防膀胱移行细胞癌术后复发的药物。
Objective To observe the effect of hypergammastrin infusion on the prevention of recurrent bladder transitional cell carcinoma. Methods Totally 43 cases of bladder transitional cell carcinoma (217 cases) undergoing bladder surgery were treated with intravesical instillation of hyper-mesenteric cardioplegia and compared with other drug infusion therapy during the same period. Results All 43 cases were followed up for 3 to 30 months with an average follow-up period of 15 months and 8 cases of recurrence. The recurrence rate was 18.6%. There was no significant difference in the prevention of other drug infusion during the same period. Complications and complications Small reaction. Conclusion Polygalacturon is a kind of effective drug to prevent postoperative recurrence of bladder transitional cell carcinoma.