拟除虫菊酯类杀虫剂(Pyr-th ond nsecticides)是七十年代中期迅速发展起来的一类人工合成化学农药,具有广谱、高效的杀虫活性。随着近几年来在我国的推广使用,已有多起临床中毒的报道。轻者出现头晕、恶心、呕吐、流涎、面部胀麻;重者有肌束震颤、肢体颤抖、抽搐、意识障碍,甚至死亡。对于此类农药中毒,目前尚缺乏安全特效的解毒药,仍以对症治疗为主。为了寻找有效的拮抗药物,国内外对拟除虫菊酯中毒进行了一些实验治疗 Pyrthion insecticides (Pyr-th ond nsecticides) is a kind of synthetic chemical pesticide that developed rapidly in the mid seventies. It has broad spectrum and high insecticidal activity. With the promotion and use in our country in recent years, there have been many reports of clinical poisoning. Light appeared dizziness, nausea, vomiting, salivation, facial distending; severe cases of fasciculation tremor, limb trembling, convulsions, disturbance of consciousness and even death. For such pesticide poisoning, the current lack of safe special effects antidote, still symptomatic treatment based. In order to find effective antagonistic drugs, pyrethroid poisoning at home and abroad conducted some experimental treatment