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目的观察三种抗生素治疗方案对老年肺部感染的疗效以及感染指标变化,以探究如何更加合理使用抗菌药物。方法选取2014年4月~2015年6月我院收治的老年肺部感染住院患者86例作为研究对象,将其随机分为拉氧头孢组38例、头孢西丁21例与头孢匹胺患者27例,分别使用拉氧头孢、头孢西丁、头孢匹胺进行治疗,并观察各自的疗效和感染指标变化。结果三种药物治疗老年肺部感染均显示出较好的疗效,其中拉氧头孢组在症状改善和部分感染指标下降方面均优于其他两组,差异有统计学意义(P<0.05),结论老年肺部感染有其特殊性,在治疗时要同时兼顾覆盖革兰氏阴性菌和厌氧菌,而拉氧头孢具备了相应的药理学特性,显示出较好的疗效,值得推广应用。
Objective To observe the curative effect of three kinds of antibiotic treatment regimen on senile pulmonary infection and the change of infection index in order to explore how to use antibiotics more reasonably. Methods Totally 86 elderly hospitalized patients with pulmonary infection in our hospital from April 2014 to June 2015 were selected as study subjects and randomly divided into three groups: control group (n = 38), cefoxitin group (n = 21) and cefpiramide group (n = 27) Cases, respectively, the use of dexamethasone, cefoxitin, cefpiramide for treatment, and observe their efficacy and changes in infection indicators. Results All the three drugs showed good efficacy in the treatment of senile pulmonary infection. Among them, the rate of improvement of symptoms and the decrease of some indicators of infection were better in the two groups (P <0.05). Conclusions Elderly pulmonary infection has its own particularity, both in the treatment of both Gram-negative bacteria and anaerobic bacteria covered, and pull the oxygen capsule has the corresponding pharmacological properties, showing good efficacy, it is worth promoting the application.