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用油酸（０．１ｍｌ／ｋｇ）及大肠杆菌（６．０×１０９／ｋｇ）分别注入大鼠，２小时后用激素或庆大霉素治疗，第８天取血和肺，分别进行病理学和免疫学检查。光镜下见肺小血管内中性粒细胞浸润、肺间质水肿、灶性肺不张，油酸组还出现肺灶性纤维化。血浆和肺组织匀浆中测得的肿瘤坏死因子显著增加。而治疗组与对照组的病理改变和测得肿瘤坏死因子经统计学处理后表明，激素可以明显减轻油酸或大肠杆菌所致大鼠的肺损伤。
Rats were injected with oleic acid (0.1 ml / kg) and Escherichia coli (6.0 × 109 / kg) respectively. Hormone or gentamicin was administered after 2 hours. Blood and lungs were taken on day 8, Neo-Confucianism and immunology. Light microscopic pulmonary vascular neutrophil infiltration, pulmonary interstitial edema, focal atelectasis, oleic acid group also appeared in pulmonary fibrosis. Tumor necrosis factor as measured in plasma and lung homogenates increased significantly. The pathological changes in the treatment group and the control group and the measured tumor necrosis factor by statistical analysis showed that hormones can significantly reduce the oleic acid or E. coli-induced lung injury in rats.