BERH-2肝癌大鼠红细胞膜K~+依赖性磷酸酶活性与正常大鼠无显著差异。但是,K~+对酶的变构激活及F~-对酶的变构抑制却差别显著,其Hill系数不同于正常大鼠。此差别在0.10mg/ml Triton X-100存在时消失,因此,Hill系数的差异可能由于BERH-2肝癌大鼠红细胞膜中脂质成分与正常的不同所致。 BERH-2 hepatoma rats erythrocyte membrane K ~ + -dependent phosphatase activity and normal rats no significant difference. However, K ~ + allosteric activation of the enzyme and F ~ - inhibition of the enzyme allosteric significant difference, the Hill coefficient is different from normal rats. This difference disappears in the presence of 0.10 mg / ml Triton X-100, so the difference in the Hill coefficient may be due to the normal difference in lipid composition in the erythrocyte membrane of BERH-2 hepatoma rats.