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目的观察参芪扶正注射液联合醋酸甲地孕酮改善晚期肺癌患者生存质量。方法将80例晚期肺癌患者分两组,对照组支持对症治疗为主,治疗组在其基础上增加参芪扶正注射液联合醋酸甲地孕酮,每6周为1个疗程,评价疗效。结果治疗组有效率为72.7%,对照组有效率为44.4%,两组比较有统计学差异(P<0.05)。对照组出现静脉炎、口干、皮疹等不良反应,治疗组出现颜面潮红、静脉炎、口干、恶心等毒副反应。结论在对症治疗基础上给予参芪扶正注射液联合醋酸甲地孕酮在改善肺癌晚期生存质量方面取得较好的疗效,值得推广。
Objective To observe the Shenqifuzheng injection combined with megestrol acetate in improving the quality of life of patients with advanced lung cancer. Methods Eighty patients with advanced lung cancer were divided into two groups. The control group supported the symptomatic treatment. The treatment group added Shenqi Fuzheng injection combined with megestrol acetate every 6 weeks to evaluate the curative effect. Results The effective rate was 72.7% in the treatment group and 44.4% in the control group, with statistical significance (P <0.05). The control group appeared phlebitis, dry mouth, rash and other adverse reactions, the treatment group appeared facial flushing, phlebitis, dry mouth, nausea and other toxic reactions. Conclusion On the basis of symptomatic treatment, Shenqi Fuzheng injection combined with megestrol acetate has good efficacy in improving the quality of life of advanced lung cancer, which is worth promoting.