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例1、2:均为男性,年龄分别为6岁、8岁,入院前5小时误服芬氟拉明片分别为12片、5片(每片20g)。服药2小时后均出现恶心、呕吐及抽搐,呕吐为非喷射状,抽搐为持续性伴阵发性加剧,同时神志模糊。体检:体温均为38℃,神志恍惚、面色苍白,例1呈抽搐状态。2例双侧瞳孔均为0.6cm,光反应存在,心肺检查正常,肠鸣音亢进,颈部有抵抗感,双侧巴彬斯基征阳性,布鲁金斯基征及克匿格征阴性,双侧膝反射消失,不能站立。均作脑脊液、头颅CT、脑电图、肝、肾功能、心电图、血、尿常规检查,除例1脑电图轻度异常外余均正常。2例用鲁米那和安定抗惊厥及补液治疗。1小时后抽搐逐步缓解,但仍较兴奋。2例双侧瞳孔分别在15小时及12小时后缩至0.2cm.例148小时后巴彬斯基征阴性、双膝反射恢复并能站立。例240小时巴彬斯基征阴性,15小时双侧膝反射恢复并能站立行走。2例均愈。 例3:男性,7岁,入院前5小时误服芬氟拉明2片。服药后3小时有呕吐,胸闷。体检:体温37℃,神志
Cases 1 and 2: All men, aged 6 years and 8 years old. Five hours before admission, fenfluramine tablets were 12 and 5 tablets (20g each). 2 hours after taking medication were nausea, vomiting and convulsions, vomiting non-jet-like, convulsions for persistent with paroxysmal exacerbation, at the same time ambiguity. Physical examination: body temperature are 38 ℃, trance, pale, Example 1 convulsions. Two cases of bilateral pupil were 0.6cm, light response exists, heart and lung examination was normal, hyperactive bowel sounds, neck resistance, bilateral Babinski sign positive, Brookings-based sign and Keweige negative , Bilateral knee reflex disappeared, can not stand. All cerebrospinal fluid, head CT, EEG, liver, kidney function, ECG, blood, urine routine examination, except for cases of mild abnormal EEG abnormalities were normal. 2 cases with luminal and diazepam and rehydration therapy. Twitch gradually relieved after 1 hour, but still more exciting. Two cases of bilateral pupil shrink to 0.2 cm at 15 hours and 12 hours, respectively. After 148 hours, Babinski’s sign was negative and his knees reflexed and stood up. Cases of 240-hour Babinski sign negative, 15-hour bilateral knee reflex and can stand to walk. 2 cases were cured. Example 3: Male, 7 years old, 2 hours before admission, taking fenfluramine 2 times. 3 hours after taking vomiting, chest tightness. Physical examination: body temperature 37 ℃, consciousness