用 ELISA 法对武汉市部分托幼机构1～7岁的510名儿童进行了抗-HBs 水平测定。平均阳性率为66.47％,接种1、2、3针组分别为51.72％、65.52％,72.12％,未接种组为34％。接种3针的效果明显优于接种1针者,接种与未接种组相比,免疫效果指数为2.0(?),抗体保护率为69.56％,表明乙肝疫苗漏种和非全程接种比例仍较大,接种后的抗-HBs 阳转率低于国内外文献报导水平。 Anti-HBs levels were measured in 510 children aged 1 to 7 years in some nurseries in Wuhan by ELISA. The average positive rate was 66.47%, 51.72%, 65.52% and 72.12% in the first, second, and third inoculation groups, respectively. Inoculation 3-needle significantly better than vaccination 1 needle vaccination and non-vaccinated group, the immune effect index was 2.0 (?), Antibody protection rate was 69.56%, indicating that hepatitis B vaccine leakage and non-full vaccination proportion is still large , The positive rate of anti-HBs after inoculation was lower than that reported in the literature at home and abroad.