杀灭血吸虫中间宿主螺蛳的药物,一般对鱼类有较高的毒性。目前广泛使用的氯硝柳胺,别名贝螺杀和三苯甲基吗啉,其有效的杀螺浓度对鱼类都有毒性。由于杀螺剂的使用,引起了水源污染和影响鱼业生产等问题。因此指望有高效低毒的杀螺剂。以前常用不同种的鱼类进行药物毒性试验,但尚无标准实验方法。鉴于尖头小鲦鱼(guppy)饲养在20～25℃的水中可全年生长繁殖,获得幼鱼, Drugs that kill the intermediate host snail of schistosomiasis are generally more toxic to fish. The currently widely used niclosamide, alias shell snail and trityl morpholine, its effective concentration of snail toxicity of fish. As a result of the use of narcotics, water pollution has been caused and problems affecting fish production have been raised. Therefore, expect to have efficient and low toxicity of snail agents. Different kinds of fish were used for drug toxicity test before, but there is no standard test method. As guppy is kept in 20-25 ℃ water for annual growth and reproduction, juveniles are obtained,