尿毒症钙化小动脉病导致的皮肤坏死

来源 :世界核心医学期刊文摘(皮肤病学分册) | 被引量 : 0次 | 上传用户:qiminfenglin1
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Background: Calcific uremic arteriolopathy is a rare and serious disorder characterized by systemic medial calcification of the arteries and tissue ischemia. Most often it is found inpatients with chronic renal failure on dialysis and in renal transplant recipients with secondary hyperparathyroidism. Methods: We report six patients with end-stage renal disease [five on hemodialysis (one with a nonfunctioning renal graft) and one on peritoneal dialysis] abstract who developed painful livedo reticularis and skin necrosis of the limbs. All had secondary hyperparathyroidism and elevated calcium-phosphorus product. Our patients presented with the following clinical features: white race (six patients), hypoalbuminemia (three patients), diabetes (one patient), and obesity (four patients). Results: Subtotal parathyroidectomy was performed in three cases. Despite this procedure, two patients died; one patient survived and his lesions healed. One patient was treated with aggressive wound care and hemodialysis (with low dialysate calcium concentration and Renagel phosphorus binders) and one patient received only local wound care, both with improvement of their lesions. In one case, no therapy was performed because the patient died immediately after diagnosis. Conclusions: The three patients who survived (Cases 4, 5 and 6) had distal lesions, normal serum albumin, and an early diagnosis. There was a relationship between the outcome of the patients and these factors, rather than the type of treatment received. Background: Calcific uremic arteriolopathy is a rare and serious disorder characterized by systemic medial calcification of the arteries and tissue ischemia. Most often it is found inpatients with chronic renal failure on dialysis and in renal transplant recipients with secondary hyperparathyroidism. Methods: We report six patients with end-stage renal disease [five on hemodialysis (one with a nonfunctioning renal graft) and one on peritoneal dialysis] abstract who developed painful livedo reticularis and skin necrosis of the limbs. All had secondary hyperparathyroidism and elevated calcium-phosphorus product. Our patients presented with the following clinical features: white race (six patients), hypoalbuminemia (three patients), diabetes (one patient), and obesity (four patients). Results: Subtotal parathyroidectomy was performed in three cases. One patient survived and his lesions healed. One patient was treated with aggressive wound care an dhemodialysis (with low dialysate calcium concentration and Renagel phosphorus binders) and one patient received only local wound care, both with improvement of their lesions. In one case, no therapy was performed because the patient died immediately after diagnosis. Conclusions: The three patients who was alive (Cases 4, 5 and 6) had distal lesions, normal serum albumin, and an early diagnosis. There was a relationship between the outcome of the patients and these factors, rather than the type of treatment received.
其他文献
日前,辽宁省庄河市养殖的千余亩中国对虾新品种“黄海2号”顺利通过中国水产技术推广总站专家组的现场验收,其中精养池17尾对虾重500克;虾参混养池16.3尾对虾重500克,平均亩
我们于2002年4月至2004年6月应用输尿管镜双频双脉冲激光碎石术(U100L)和体外冲击波碎石(ESWL)治疗输尿管结石369例,对两者疗效进行比较。
The expressed sequence tags (ESTs) of Japanese flounder, Paralichthys olivaceus, were selected from GenBank to iden-tify simple sequence repeats (SSRs) or micro
前列腺增生症(BPH)是中老年男性泌尿系统最常见的疾病之一,发病率随年龄递增。药物治疗及传统的手术切除存在疗效差或手术风险大的缺点。经尿道选择性磷酸钛氧钾晶体(KTP)激
肾功能衰竭的男性患者常常伴有勃起功能障碍(ED),并且在患者接受肾移植手术后,ED也并不总能得到改善,因此往往需要针对ED进行有效的治疗。枸橼酸西地那非是应用广泛的治疗ED
1.快!快!快!一切要快,除了做爱。前面三个字,写在我的橙色冲锋衣背后,写在我的橙色摩托车上,还写在我的橙色挎包与橙色棒球帽上。后面一句话,哈,是玩笑,当然不必写,那是常识
去年入夏以来,东平湖网箱养殖鳜大面积暴发一种以充血、出血和肝胆病变为主要特征的暴发性疾病,给许多养殖户造成了近乎毁灭性的打击。 Since the summer of last year, the
文学界习惯把电视剧本创作称为触电,记忆中,上个世纪90年代初我就触电去了。当时我的小说创作正在势头上,《腊月》、《乡长》、《汇跷》、《出民工》等一批中短篇小说已经引
第一章总则第一条为进一步规范全国渔业统计工作,保证渔业统计资料的真实性、准确性、完整性和时效性,根据《中华人民共和国统计法》及其实施细则和《统计违法违纪行为处分规
我司是国家级对虾良种场(在建)、广东省省级对虾良种场、广东省高新技术企业、广东省健康农业科技示范基地、广东省星火技术产业带建设示范单位、广东省农业科技创新中心(在