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目的:分析系统性红斑狼疮（SLE）患者压力感知的危险因素，构建并验证SLE患者健康危险性压力感知的风险预测模型。方法:本研究为横断面研究。选取2020年10月—2021年3月安徽省4所综合性医院风湿免疫科住院及门诊的310例SLE患者为建模对象，根据患者压力感知评分分为有健康危险性压力组（n n=132）和无健康危险性压力组（n n=178），将两组的一般资料、狼疮疾病活动度、一般自我效能感、情绪智力、心理弹性、睡眠障碍、焦虑、抑郁等进行比较，筛选出独立危险因素并利用Logistic回归进行风险预测模型的构建，采用Hosmer-Lemeshow和受试者工作特征曲线下面积分别检验模型的拟合度和预测效果，并纳入206例患者进行模型验证。n 结果:二项Logistic回归分析显示，SLE疾病活动度、心理弹性、焦虑、支付类型、家庭月收入是SLE患者压力感知的影响因素（n P<0.05）。Hosmer-Lemeshow拟合度检验显示χn 2=6.123，n P=0.633；受试者工作特征曲线下面积为0.903，约登指数最大值为0.660，预测临界值为0.497，敏感度为0.795，特异度为0.865。n 结论:该研究基于SLE疾病活动指数、心理弹性、焦虑、支付类型、家庭月收入5项SLE患者压力感知产生的独立危险因素构建的风险预测模型具有良好的敏感度与特异度，可为临床评估SLE患者健康危险性压力感知提供借鉴。“,”Objective:To analyze the risk factors of stress perception in patients with systemic lupus erythematosus (SLE) , and construct and validate a risk prediction model for health risk stress perception in SLE patients.Methods:This study is a cross-sectional study. From October 2020 to March 2021, totals of 310 SLE inpatients and outpatients in the Department of Rheumatology and Immunology from 4 general hospitals in Anhui Province were selected as the modeling object. According to the patients\' stress perception score, they were divided into the group with health risk stress (n n=132) and the group without health risk stress (n n=178) . The general data, SLE disease activity, general self-efficacy, emotional intelligence, resilience, sleep disturbance, anxiety, depression were compared between the two groups, and independent risk factors were screened out and Logistic regression was used to construct a risk prediction model. Hosmer-Lemeshow and receiver operator characteristic curve (ROC) area were used to test the fit and prediction effect of the model, respectively, and 206 patients were included for model validation.n Results:Binary Logistic regression analysis showed that SLE disease activity, resilience, anxiety, payment type, and family monthly income were the influencing factors of stress perception in SLE patients, and the difference was statistically significant (n P<0.05) . Hosmer-Lemeshow fit test showed χn 2=6.123, n P=0.633. Besides, the area under the ROC, maximum Youden index, predictive critical value, sensitivity and specificity were 0.903, 0.660, 0.497, 0.795 and 0.865 respectively.n Conclusions:This study is based on five independent risk factors of SLE patients\' stress perception, namely SLE disease activity, resilience, anxiety, payment type, and family monthly income. The risk prediction model has good sensitivity and specificity, which can provide a reference for clinical assessment of health risk stress perception in SLE patients.